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Online ISSN : 2349-8080 Issues : 12 per year Publisher : Excellent Publishers Email : editorinchiefijcrbp@gmail.com |
The emergence of various diseases mainly, noncommunicable diseases is a menace worldwide. Hence the plant-based medicines and drugs have gained attention recently. Muntingia calabura is one of the plants that possess anti-inflammatory, antioxidant, and pharmacological properties. Various parts of the plants, especially leaves, have various health benefits, which is still not explored completely. Hence the current study focuses on the phytochemical constituents, antioxidant and anti-microbial properties of M. calabura leaves. Identification of secondary metabolites which have potent antioxidant properties and medicinal value is much more essential for treatment of various health hazards. M. calabura possesses remarkable medicinal value, which warrants further and in-depth studies in the future. This plant is widely used in traditional medicine, in which almost all parts are utilized as it has the best antioxidant potential for cardiovascular diseases. The preliminary analysis of phytochemicals showed the presence of some beneficial phytochemicals such as terpenoids, flavonoids, tannins, and alkaloids The results obtained by the determination of phenolics showed the highest concentration of phenolics in the aqueous extract. The results of total antioxidant activity clearly showed that the acetone extract has the highest antioxidant activity. Among various extracts, alcoholic extracts of 10 mg/ml and acetone extracts of 5 mg/ml and 10 mg/ml showed potential antibacterial activity against E. coli and in Bacillus cereus, alcohol and acetone extracts showed better zone of inhibition. The findings of this study provided the evidence of leaf extract possessing antioxidant activity and the presence of phytochemicals, exhibiting the potential fora wide range of therapeutic properties which can be used in manufacturing medicines and drugs.
