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Abstract                 Volume:11  Issue-9  Year-2024          Original Research Articles

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Comparative study of in-vitro and ex-vivo activities of a bioactive compound from Aloe vera plant - A therapeutic compound on zebra fish
J. Subashini, A. R. Nithiyashri, G. Charumathi, K. Nagalakshmi*
Department of biotechnology, Karpaga Vinayaga College of engineering and technology, Chinna kolambakkam, Maduranthagam-603308, Tamil Nadu, India
*Corresponding author
Abstract:

Aloe vera is a medicinal plant with a traditional history, complex constituents, and various pharmacological activities. In India, it is found in Maharashtra, Gujarat, Rajasthan, Tamil Nadu, and Andhra Pradesh. Aloe vera is also called the wand of heaven, potted physician, wonder plant, plant of life, and heaven’s blessing. Aloe vera contains vitamins A, B12, C, and E, choline, folic acid, minerals, sugars, amino acids, and sterols. The pulp gel of Aloe vera works as an antivirus, antibacterial, antifungal, anti-cancer, and wound healing, with the medicinal principles being phenolics and polysaccharide compounds. In this study, with the objective of the production of not only healthy but also standardized sizes of plantlets to be used in the subsequent controlled stages of the process, Aloe vera has been analyzed for various phytochemicals and Antioxidants and standardized for the initiation of Aloe vera through micropropagation where the produced in-vitro plants were tested for the presence of phytochemicals and antioxidants along with the efficiency of anti-microbial activity against the ex-vivo plants proving the quality and success of micropropagation. The zebrafish is an important model which has 84% of gene similarities and 70% of disease similarities. Here we use adult zebrafish as a model organism in research and it is widely used in testing and understanding the study compound's pharmacology and therapeutic efficacy. The mixture was tested across behavior, locomotor, and neuromotor responses to understand the activity compound. The complete assessment procedure entails exposing adult zebrafish to the given combination for a period of 21 days and its activity is analyzed.

Keywords: Aloe vera, Antioxidants, Micropropagation Phytochemicals, Secondary metabolites, Zebrafish
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How to cite this article:

Subashini, J., Nithiyashri, A. R., Charumathi, G., Nagalakshmi, K., 2024. Comparative study of in-vitro and ex-vivo activities of a bioactive compound from Aloe vera plant - A therapeutic compound on zebra fish.Int.J.Curr.Res.Biosci.Plantbiol. 11(9): 1-14. doi: https://doi.org/10.20546/ijcrbp.2024.1109.001
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