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Online ISSN : 2349-8080 Issues : 12 per year Publisher : Excellent Publishers Email : editorinchiefijcrbp@gmail.com |
Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia due to insulin dysfunction. Effective treatment strategies focus on managing glucose levels and mitigating complications. This study explores the synthesis and application of chitosan nanoparticles (CS-NPs) as carriers for antidiabetic drugs. Chitosan, derived from chitin, was used due to its biocompatibility and biodegradability. The nanoparticles were characterized using UV-visible spectroscopy, scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR). Encapsulation of the antidiabetic drug within the nanoparticles enhanced drug stability and activity. Results demonstrated that CS-NPs significantly improved α-amylase inhibition and maintained high cell viability, making them a promising tool for antidiabetic therapy.
