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Online ISSN : 2349-8080 Issues : 12 per year Publisher : Excellent Publishers Email : editorinchiefijcrbp@gmail.com |
Cissus belongs to Vitaceae family and it was classified into 13 distinct genera. Among these species, Cissus quadrangularis Linn commonly known as Asthisamharaka found in hottest region of India, it has more potential applications in various fields, including medicine, agriculture, and industry. Cissus quadrangularis is a perennial plant native to Asia and Africa, known for its medicinal properties. It's often used in traditional medicine to treat various ailments such as bone fractures, joint pain, and digestive issues. Research suggests it may have anti-inflammatory and bone-healing properties, making it popular in supplements for athletes and those with bone-related conditions. However, more studies are needed to fully understand its effectiveness and safety. Oral pathogens are microorganisms that can cause diseases in the oral cavity. Common examples include Streptococcus mutans, which contributes to tooth decay, and Porphyromonasgingivalis, associated with periodontal disease. Properoral hygiene and regular dental check-ups are crucial for preventing these pathogens from causing harm. Phytochemical analysis has unveiled aplethora of bioactive compounds within Cissus quadrangularis, including flavonoids, triterpenoids, phytosterols, and various minerals. Cissus have diverse pharmacological activities, which encompass anti-inflammatory, analgesic, antioxidant, anti-osteoporotic, anti-diabetic, and anti-obesity effects. Qualitative analysis is done to identify the phytochemicals present in the different extract of source and quantitative analysis has done for the estimation. Then the extract was screened for its anti-inflammatory activity by the method of inhibition of denaturation. The results show increase in the concentration of extract increases the inhibition percentage. Chromatographic techniques are done to find which ratio of concentration of solvents elutes efficiently. By the results, 7:3 ratio of benzene extract of Cissus quadrangularis elutes efficiently at Rf value of 0.86 respectively. The benzene extract of Cissus quadrangularis shows best result in FT-IR analysis. The peak value of the FT-IR 3400 shows possible compounds are alkene and alcohol.
