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Online ISSN : 2349-8080 Issues : 12 per year Publisher : Excellent Publishers Email : editorinchiefijcrbp@gmail.com |
Emulgel is an emerging drug delivery system. The emulgel was prepared by using carbonol 934 and emulsified agent ratio (span: tween) for geometric and homogenous mixing of all the excipients and the plant extracts. By using slab technique, we have developed five batches of our emulgel, namely F1, F2, F3, F4 and F5 From% drug diffusion study it was observed that, the preparation topical PPE emulgel formulation released a maximum of 83.56 ± 0.544% over a period of 6 hours. The studies of the prepared emulgel were carried out for 60days by keeping at 25°C ±2°C/60%R H 5%±5%, 32°C±2°C and 60%RH±5%R Hand 40°C±2°C and 75%±5% relative humidity (RH). The results indicated different parameters like PH, viscosity, no phase separation and no significant changes in physical appearance, spredability and drug content observed when compared with the initial formulations, F4 contain maximum result when compared to others. The in-vitro release kinetics reveals that all the formulations fit well with zero order kinetics followed by non-Fickian type mechanism.
