Online ISSN : 2349-8080 Issues : 12 per year Publisher : Excellent Publishers Email : editorinchiefijcrbp@gmail.com |
2 Bioinformatics Division, The Biome, Kolkata-700 064, India
3Department of Botany, Bangabasi Evening College, Kolkata-700 009, India 4Theoretical and Computational Biology Division, Amplicon Institute of Interdisciplinary Science and Technology,Palta-743 122, India
Ebola has been identified to be one of the most ominous pathogens capable of causing pandemic fatal disease in humans. Efforts are on to control the pathogen using various different therapeutic techniques and the vaccination effort is in its early second phase according to WHO sources. However, whether the candidate vaccine can confer “herd immunity” to a particular population remains a doubt. Thus alternative therapeutic approaches should be continuously explored, so as to combat the spread of the disease. In this work we attempt to identify one of the most predominant and essential RNA structural motifs - pseudoknot in the entire Ebola genome. The results indicate that a conserved pseudoknot motif is present in between the intergenic regions in between VP 24 and VP 30.