Abstract                 Volume:5  Issue-3  Year-2018          Original Research Articles

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Extraction, Isolation and Characterization of Maerua oblongifolia (‘Sanagana’)
Desta Ekero1*, Mebratu Legesse2, Alemu Lelago3 and Mathewos Agize
1 & 4 College of Natural and Computational Sciences, Wolaita Sodo University, Ethiopia
2 College of Public and Medicine, Wolaita Sodo University, Ethiopia
*Corresponding author
Abstract:

Maerua oblongifolia was among other medicinal plants those were extensively used medicinal plants for treatment of human and domestic animals in addition to serving as detergent for washing purpose.The present study was developed to contribute to the documentation of the pharmacological and biological activity testing through extraction, isolation, and characterization of crude extracts of leaves of most popularly used traditional medicinal plant, Maerua oblongifolia. Air dried leaf powder of Maerua oblongifolia was exhaustively extracted with methanol at room temperature. Fractionation of the column elution started with 30 ml of pure diethyl ether, followed by increasing polarity of solvent system, diethyl ether, ethylacetate, ethanol, methanol, water, 32 fractions were collected. This study has resulted in the isolation and characterization of MOM-19.Characterization was done by spectroscopic technique, Nuclear Magnetic Resonance (NMR).The 13C NMR spectrum of the compound showed well resolved resonance of 38 carbon atoms. The number of carbon atom indicated that it was a triterpene. The result of this study was important as the search for new pharmacologically active compounds from plant extracts that may led to the discovery of many clinically useful drugs.

Keywords: Fractionation,Maerua oblongifolia,Medicinal plant,Pharmacological activity,Spectroscopic analysis
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How to cite this article:

Desta Ekero, Mebratu Legesse, Alemu Lelago, Mathewos Agize, 2018. Extraction, isolation and characterization of Maerua oblongifolia (‘Sanagana’).Int.J.Curr.Res.Biosci.Plantbiol. 5(3): 42-48. doi: https://doi.org/10.20546/ijcrbp.2018.503.006