 |
Online ISSN : 2349-8080 Issues : 12 per year Publisher : Excellent Publishers Email : editorinchiefijcrbp@gmail.com |
Cultivation of Rabies Virus Strain of the “Kazsrvi” in Cell Culture
Kazakh Scientific Research Veterinary Institute, Almaty, Republic of Kazakhstan
*Corresponding author
Abstract:
The article presents the results of cultivation of the laboratory strain of rabies virus in the cell cultures of BHK-21 and TN-KK49 in successive passages, which was carried out in different ways. In one case the passages was performed by transferring of infected cell cultures, in the other case - by introducing to the new batch of intact cells the suspension of infected cell cultures of the previous passage. It was established that both kinds of used cell culture are susceptible to rabies virus and it can be passaged in these substrates tested with these both ways. The cultural virus of the third passage preserves its pathogenicity with respect to mice at intracerebral infection.
Keywords: Infection Passage Rabies virus Substrates Suspension
Download this article as 
How to cite this article:
Myrzakhmetova, B.Sh., Kutumbetov, L.B., 2017. Cultivation of rabies virus strain of the “Kazsrvi” in cell culture.Int.J.Curr.Res.Biosci.Plantbiol. 4(9): 24-28. doi: https://doi.org/10.20546/ijcrbp.2017.409.005
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.