Abstract                 Volume:4  Issue-3  Year-2017          Original Research Articles

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Study of Effectiveness of Serum Electrolytes and Inorganic Elements as Biomarkers in Acute Myocardial Infarction Patients
M. K. Ismail1*, L. A. Mustafa2 and A. S. Karanghadan3
1,3Department of Biomedical Sciences, Gulf Medical University, Ajman, United Arab Emirates
2Department of Chemistry, College of Science, University of Mosul, lraq
*Corresponding author

The present study focused on the effectiveness of serum electrolytes and inorganic elements as risk and illness indicators in acute myocardial infarction (AMI) patients. Data from 317 male and female subjects with ages of 34-87 years is used in the study. The results indicated a significant decrease in serum Na+, K+ and Cl- of AMI patients with a p˂0.001 compared to healthy subjects. Furthermore, concentrations of Mg2+ and Cu2+ increased significantly in those patients while those of Ca2+, Zn2+ and Se decreased at the level of p˂0.001. The cutoff values for the electrolytes and different inorganic elements were also estimated by calculating the sensitivity, specificity and efficiency for each of the parameters. The values of the specificity and sensitivity were used to evaluate the effectiveness of electrolytes andinorganic elements both as risk factor and markers for AMI. Among the electrolytes, Na+ and K+ showed the best characteristics with Sn = 100%, SP = 85% and Ef = 96% at the 95th percentile. Among the inorganic elements, Zn2+ showed the best characteristics with Sn = 100%, SP = 100% and Ef = 100% at the 95th percentile followed by Se with Sn = 70%, SP = 100% and Ef = 79%.

Keywords: Acute myocardial infarction,Cardio vascular diseases,Biomarkers,
Electrolytes,Inorganic elements
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How to cite this article:

Ismail, M. K., Mustafa, L. A., Karanghadan, A. S.,  2017. Study of effectiveness of serum electrolytes and inorganic elements as biomarkers in acute myocardial infarction patientsInt.J.Curr.Res.Biosci.Plantbiol. 4(3): 57-63. doi: https://doi.org/10.20546/ijcrbp.2017.403.006